皮膚結締組織與骨科
隨著環境的改善，人類的壽命延長，有越來越多因老化衍生出的健康問題，例如骨質疏鬆以及糖尿病。目前的骨鬆藥大多有副作用而無法長期服用。因此利用疾病動物模式來模擬骨鬆現象，對於找出新的治療方法將有莫大的幫助。另外，以糖尿病來說，大面積的燒燙傷傷口、長期臥床的褥瘡傷口和糖尿病患者傷口不易癒合的問題等，也都是有待解決的困境。
我們目前建議提供的模式動物有：
| Disease | Model | Phenotype |
| Osteoporosis | Glucocorticoid-induced osteoporosis (daily injection of dexamethasone (2 mg/kg/day) for 4 weeks |
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| Osteoporosis | postmenopausal osteoporosis created by ovariectomy with low calcium diet |
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| Diabetic wound healing | Three popular models that can be used to study diabetic wound healing: (1) type II diabetic db/db mouse; (2) type I streptozotocin (STZ)-induced C57BL/6J mouse and (3) C57/BL6 mouse induced with high fat diet. The cutaneous wound healing utilizes punching methods to create circular full thickness wounds on the dorsum of mice (critical wound sizes ranges from 7 to 10 mm in diameter) |
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